Normally there is a small but noticeable drop in quality, but this is HUGE! and attached is the file off XSplit https://1drv.ms/u/s!Aoi1voX-EdDmhNZjCrIDvgSsKOIq-Q
Doesn't look too bad to me, but a workaround is to render your 1080p video as 1440p. Even though that won't magically make the video higher resolution, Youtube will see it as 1440p and offer less compression so it still ends up cleaner than a normal 1080p upload. Also, tons of moving objects on screen (the rain particles in yours) will usually cause compression techniques to crap out a bit as it essentially has to update every pixel every frame, as opposed to when there's little movement it can keep things static until it's necessary to move.
The rain effect is means you're stretching your bitrate budget really, really far and so your quality suffers. Let's also consider that the video would have to have been compressed at least three times, first by the recording software, then your editing software, then Youtube itself.
Yeah, the quality drops significantly when I leave the cockpit and the rain effect is all over the video. Didn't bother with editing, just from recording siftware which used NVENC (shadowplay encoder). I supposse I should stop moaning, uploading in higher resolutions takes more time and Virgin Media have woeful upload speeds 150/10 is my connection